dibutyldimethylurea

• dibutyldimethylurea is a synthetic urea derivative characterized by two butyl and two methyl groups attached to a central urea structure. it is a chemically modified compound with reported antimicrobial and antifungal properties, and has been identified in the root extracts of certain medicinal plants. although not naturally abundant, it may serve as a lead compound for developing new antibacterial agents.

  • chemical properties

    • molecular weight: 230.37 g/mol
    • structure: symmetrical urea molecule substituted with two butyl and two methyl groups
    • appearance: white to off-white crystalline solid (depending on purity)
    • solubility: soluble in organic solvents such as ethanol, ether, and chloroform; poorly soluble in water
    • chemical formula: C₁₀H₂₂N₂O

  • usefulness in medicine

    • dibutyldimethylurea has shown potential antimicrobial activity in early screening studies.
    • it may act as a membrane disruptor or enzyme inhibitor, although its mechanism is not well-characterized.
    • due to its urea backbone, it may be investigated for urease inhibition in microbial pathogens.
    • its bioactivity is of interest in natural product chemistry and drug development from plant-derived compounds.

  • antibacterial and antimicrobial activity

    • it has been shown to inhibit growth of certain gram-positive and gram-negative bacteria in vitro.
    • some studies suggest potential action against fungal pathogens such as candida species.
    • may work synergistically with other phytochemicals in plant extracts.
    • research highlights:
      • bacteria:
        • escherichia coli research link
        • bacillus subtilis research link
      • fungi:
        • candida albicans research link

• research links

  • dibutyldimethylurea antimicrobial activity
  • urea derivatives in drug discovery
  • plant-derived urea compounds